3th WCSET-2014 at Nepal

 

Special Session at Ho Chi Minh City University of Technology, Vietnam:

Title:           Environmental Risks of Some Non-steroidal Anti-inflammatory Drugs (NSAIDs) in Surface Water in Ho Chi Minh City, Vietnam
Authors:       Do Vu Hoang Anh, Bui Quang Minh, Pham Hong Nhat
Abstract:     An environmental risk assessment of some common NSAIDs including ketoprofen, ibuprofen, diclofenac sodium and mefenamic acid for surface water in Ho Chi Minh City was performed by determination of their concentrations in water environment (MEC). Risk levels were obtained from the comparison between the MEC value and predicted no-effect concentration (PNEC). Analysis results of the surface water samples collected in Ho Chi Minh City during September, October and November 2013 showed that the environmental risk levels of ketoprofen, ibuprofen and diclofenac sodium were not high except for ibuprofen at Le Van Sy Bridge in the first two surveys. Mefenamic acid has consistently been identified as high risk at almost all sampling sites. The total risk level of the 4 compounds in surface water in Ho Chi Minh City has been found at high risk levels.According to the hazard index (HI) values calculated from chronic daily intake (CDI) and reference dose (RfD), however, it is clear that the studied compounds at the existing concentrations cannot pose negative impacts on human health even if the surface water is used for domestic water supply purpose. In the long run, however, if the use of these compounds increase and no proper management measures are applied, their residues in surface water may become a serious problem.

Keywords:   Environmental Risk Assessment, Non-Steroidal Anti-Inflammatory Drugs (Nsaids), Surface Water
Pages:         724-727

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